Dr. D. Julie Carrier
Professor
Biological and Agricultural Engineering
Office: ENGR 227
Phone: (479) 575-4993
Fax: (479) 575-2846
E-mail: carrier@uark.edu
Education
- B.S., Agricultural Engineering, McGill University
- M.E., Chemical Engineering, McGill University
- Ph.D., Chemical Engineering, McGill University
- Post doctoral: March 1994 - July 1996 British Columbia Research Inc, Vancouver, British Columbia. (This position was stationed at the Plant Biotechnology Research Institute, Saskatoon, Canada)
- Post doctoral: September 1992 - March 1994 (NATO-NSERC) Department of Pharmacognosy, University of Leiden, The Netherlands.
Teaching and Research
Classes Taught
- 1996-1999 Principles of Plant Biological Systems, University of Saskatchewan (sophomore)
- 1999 Properties of Biological Materials, University of Saskatchewan (Junior)
- 1997-2000 Food Processing, University of Saskatchewan (senior)
- 2001-2007 Properties of Biological Materials, University of Arkansas (sophomore)
- 2002 and 2006 Food Processing, University of Arkansas (senior)
- 2003 Bioprocessing University of Arkansas (junior)
- 2002, 2005 Introduction to Biological Engineering I and II University of Arkansas (freshman)
- 2006-2007 Biological Engineering II University of Arkansas (freshman)
Biographical Information
Faculty Positions
- July 2000- current Associate-Professor Department of Biological and Agricultural Engineering, University of Arkansas
- July 1996-July 2000 Associate-Professor Department of Agricultural and Bioresource Engineering University of Saskatchewan
Industrial experience
- Research Associate, Bio-Méga Inc, Laval, Québec, Canada, September 1986 - December 1990
Awards
- FCAR (Canada) Doctoral Scholarship (1990-1991)
- NSERC-NATO (Canada) Postdoctoral Scholarship (1992-1994)
- University of Arkansas, College of Engineering, Biological and Agricultural Engineering Outstanding Service to Students Award (April 2003)
- University of Arkansas, College of Engineering, Biological and Agricultural Engineering Outstanding Teaching Award (April 2004)
- University of Arkansas, College of Engineering, Biological and Agricultural Engineering Outstanding Researcher Award (April 2006)
Committees
- 2001- Prospective Student Recruitment, University of Arkansas
- 2002 Search Committee for Chemical Engineering Department Head, University of Arkansas
- 2002 Search Committee for Engineering Dean, University of Arkansas
- 2003 College Human standards committee
- 2001 USDA S-1007 Multistate Research Committee on the science and engineering for a Biobased industry and economy
Selected Publications
Publications
- Gurley B, Swain A, Hubbard M, Williams K, Barone G, Hartsfield F, Tong Y, Carrier DJ, Cheboyina S and Battu S. (200). “Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: Effect of milk thistle, black cohosh, goldenseal, kava kava, St.John's wort and echineacea." Molecular Nutrition and Food Research (in press)
- VaughnK, McClain C, Carrier DJ, Wallace S, King J, Nagarajan S and Clausen E. (2007). “ The effect of Albizia julibrissin water extracts on low density lipoprotein oxidization”. Journal of Agricultural Food Chemistry 55: (in press).
- Bruner D, Carrier DJ, Belesky D, Pote D and Ares A. (2007). "Yield components and nutritive value of Robinia pseudoacacia and Albizia julibrissin in Arkansas, USA". Agroforestry Systems (in press)
- WallaceS, Raible J, Carrier DJ, Vaughn K, Griffis C, Clausen E and Nagarajan S. (2007). "Pressurized water rivals ethanol as a Silybum marianum extraction solvent for the initiation of copper and cell mediated low-density lipoprotein oxidation". Canadian Journal of Physiology and Pharmacology (in press)
- WallaceS, Vaughn K, Stewart B, Carrier DJ, Clausen E, Viswanthan T and Nagarajan S. (2007). " Silymarin inhibits scavenger receptor-dependent human monocyte adhesion by blocking oxidation-specific epitopes in oxidized-LDL ". Journal of Agricultural Food Chemistry (in review)
- DuanL, Carrier DJ, King J and Clausen E. “Thermal degradation of silymarin compounds in subcritical water”. Journal of Supercritical fluids (in review)
- SubramanianS, Carrier DJ and Clausen E. “Pretreatment of milk thistle seed to increase the silymarin yield: An alternative to petroleum ether defatting”. Bioresource Technology (in press)
- Vaughn K, Carrier DJ, Howard L, King J. and Clausen E. “Extraction of lycopene from watermelon using supercritical fluid extraction (SFE)”. Bioresource Technology (in review)
- LauS, Carrier DJ, Howard L, Lay J, Liyanage R, Bransby D and Clausen E. (2007). “Identification and quantification of glycoside flavonoids in the energy crop Albizia julibrissin”. Bioresource Technology 98: 429-435.
- Gurley B, Barone G, Williams K, Carrier DJ, Breen P, Yates R, Song P, Hubbard M, Tong Y, and Cheboyina S. (2006). “Effect of milk thistle (Silybum marianum) and black cohosh (Cimicifuga racemosa) supplementation on digoxin pharmacokinetics in humans”. Drug metabolism and disposition 34: 69-74.
- EkenseairA, Duan L, Carrier DJ, Bransby D and Clausen E. (2005).“ Extraction of hyperoside and quercitrin from mimosa (Albizia julibrissin) foliage". Applied Biochemistry and Biotechnology 130: 382-391.
- Gurley B, Barone G, Williams K, Carrier DJ, Breen P, Yates R, Song P, Hubbard M, Tong Y, and Cheboyina S. (2006). “Assessing the clinical significance of botanical supplementation on human cytochrome P450 3A4 activity: Comparison of a milk thistle and black cohosh product to rifampin and clarithromycin”. Journal of Clinical Pharmacology 46: 201-213.
- Bergeron C, Gafner S, Carrier DJ and Clausen E. (2005). “ Extraction of glutamine and flavonid from skullcap”. Journal of Agricultural Food Chemistry 53: 3076-3080.
- PowellE, Hill G, Juurlink G and Carrier DJ. (2005). “ Glucoraphinin extraction from Cardaria draba Part 1: Optimization of batch extraction. “ Journal of Chemical Technology & Biotechnology 80 (9): 985-991.
- Powell E, Hill G, Juurlink G and Carrier DJ. (2005). “ Glucoraphinin extraction from Cardaria draba Part 2: Countercurrent Extraction, Bioactivity and Toxicity Testing.” Journal of Chemical Technology & Biotechnology 80 (9): 992-997.
- LauS, Carrier DJ, Beitle B, Lay J, Howard L, Liyanage R and Clausen C. “Identification and quantification of glycoside flavonoids in the energy crop Kudzu”. (2005). Applied Biotechnology and Biochemistry 121-124:783-794.
- Costello T and Carrier DJ. (2006). “Emergence of Biological Engineering at the University of Arkansas”. International Journal of Engineering Education 22(6):1149-1156.
- Tanko H, Carrier DJ, Duan L, and Clausen E. (2005).“Pre and post harvesting processing of medicinal plants”. Plant Genetic Resources3: 304-313.
- Tanko H, Carrier DJ, Sokhansanj S and Crowe T. (2005). “Drying of feverfew (Tanacetum parthenium L.)”. Canadian Agricultural Biosystems Engineering47: 3.57-3.61.
- Gurley B, Hubbard M, Barone G, Tong Y, Williams D, Carrier J and Khan, I. (2005). “Assessment of milk thistle and black cohosh supplementation on digoxin pharmacokinetics”. Clinical Pharmacology and Therapeutics 77: P49.
- WallaceS, Carrier DJ, and Clausen E. (2005). “Batch extraction of nutraceuticals from Milk Thistle (Silybum marianum (L) Gaertner) using organic solvents and water”. Phytochemical Analysis 16 (1): 7-16.
- Gurley BJ, Gardner SF, Hubbard MA, Williams K, Gentry WB, Carrier J, Edwards D, Khan I, and Shah A. (2004). “In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw palmetto”. Clinical Pharmacology and Therapeutics 76 (5):428-440.
- Lau S, Carrier DJ, Howard L, Lay J, Archambault J and Clausen E. (2004). “Extraction of antioxidant compounds from energy crops.” Applied Biochemistry and Biotechnology 114: 569-584. 2
- Duan L, Carrier DJ and Clausen E. (2004). “Extraction of health beneficial compounds from milk thistle using hot/liquid water”. Applied Biochemistry and Biotechnology 114: 559-568.
- Wallace S, Carrier DJ, Beitle R, Clausen E, and Griffis C. (2003).“HPLC-UV and LC-MS-MS characterization of silymarin in milk thistle seeds and corresponding products”. Journal of Nutraceutical, Functional and Medicinal Food 4(2): 37-48.
- Alvarez Barreto J, Carrier DJ and Clausen E. (2003). “Extraction of silymarin compounds from milk thistle (Silybum marianum) seed using hot, liquid water as the solvent”. Applied Biochemistry and Biotechnology 105-108: 881-889.
- Wallace S, Carrier DJ and Clausen E. (2003). “Extraction of silymarin compounds from milk thistle (Silybum marianum) seed using solvent”. Applied Biochemistry and Biotechnology 105-108: 891-903.
- Tanko H, Carrier DJ, Sokhansanj S and Crowe T. (2003). “ Effects of drying temperature and storage on parthenolide concentration of feverfew leaves” Journal of Nutraceutical, Functional and Medicinal Food 4(1): 27-37.
- Carrier DJ, Crowe T, Sokhansanj S, Katrusiak A, Wahab J and Barl B. (2002). "Milk thistle (Sylibum marianum) flower head development and associated marker compound profile". Journal of Herbs, Spices and Medicinal Plants 10 (1): 65-74.
- Kabganian R, Carrier DJ and Sokhansanj S. (2002). “Drying of Echinacea angustifolia roots”. Journal Herbs Spices and Medicinal Plants 10 (1): 11-18.
- KabganianR, Abrams SA, Rose PA, Sokhansanj S and Carrier DJ. (2002). “Localization of marker compounds in Echinacea angustifolia”. Journal of Herbs, Spices and Medicinal Plants 10 (2):73-82.
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Kabganian, R., Carrier DJ, and Sokhansanj S. (2002).” Physical characteristics and drying rate of Echinacea root”. Drying Technology, An International Journal 20(3): 637-650.
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Alvarez Barreto J, Carrier DJ and Clausen E (2002). “Extraction of silymarin compounds from Milk Thistle (Silybum marianum)”. Discovery 3: 3-9. -
Bantle M, Crowe T and. Carrier DJ. (2001). "In situ root distribution of Echinacea angustifolia". Canadian Agricultural Biosystems Engineering 43:29 –31.
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Powell E, Carrier DJ, Crowe T, Bantle M. (2001). “Echinacoside and alkamide distribution in Echinacea angustifolia root: root depth and growing condition”. Journal of Nutraceutical, Functional and Medicinal Food 3(3): 95-106.
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Carrier DJ and Laurain D. (2000). “Plant Cell Biotechnology of Ginkgo.” In “Medicinal and Aromatic Plants - Industrial Profiles”, T. van Beek. (ed.), Harwood Academic Publishers, Amsterdam. PP 81-99.
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Carrier DJ, Kendall EJ, Bock CA, Cunningham JE and Dunstan DI. (1999). “Water content, lipid deposition and (+)-abscisic acid content in developing white spruce seeds”. Journal of Experimental Botany 50:1359-1364.
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Dunstan DI, Dong JZ, Carrier DJ, Abrams SR. (1998). "Events following ABA treatment of spruce somatic embryos". In Vitro Cell. Biol-Plant 34:159-168.
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Carrier DJ, van Beek TA, van der Heijden R, Verpoorte R. (1998). "Distribution of ginkgolides and terpenoid biosynthetic activity in Ginkgo biloba" Phytochemistry 48: 89-92.
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Carrier DJ, Bock CA, Cunningham JE, Cyr DR, Dunstan DI. (1997). "(+)-ABA content and lipid deposition in interior spruce somatic embryos". In Vitro Cell. Dev. Biol-Plant 33: 236-239.
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Carrier DJ, Cunningham JE, Taylor DC, Dunstan DI. (1997). "Sucrose requirements and lipid utilization during germination of interior spruce (Picea glauca engelmanaii complex) somatic embryos". Plant Cell Reports 16: 550-554.
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Carrier J, Archambault J, van der Heijden R and Verpoorte R. (1996). “Formation of terpenoid products in Ginkgo biloba cultivated cells". Plant Cell Reports 15: 888-891.
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Carrier DJ, Cunningham J, Hogge L, Taylor D and Dunstan D. (1995). "Gas chromatography-mass spectrometry characterization of some fatty acids from white and interior spruce”. Journal of Chromatography 715: 317-324.
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Carrier J, Chauret N, Neufeld R and Archambault J. (1994). "Ginkgo biloba L. (Maiden Hair tree)". in Biotechnology in Agriculture and Forestry, Vol. 26. Medicinal and Aromatic Plants VI, Bajaj Y. (ed.) Springer-Verlag Berlin Heidelberg, pp 136-145.
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Carrier J, Chauret N, Mancini M, Coulombe P, Neufeld R, Weber M and Archambault J. (1991). "Detection of ginkgolide A in Ginkgo biloba cell cultures" Plant Cell Reports 10: 256-259.
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Chauret N, Carrier J, Mancini M, Neufeld R, Weber M and Archambault J. (1991). "Gas chromatographic-mass spectrometric analysis of ginkgolides produced by Ginkgo biloba cell culture". Journal of Chromatography 588:281-287.
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Carrier J, Cosentino G, Neufeld R, Rho D, Weber M and Archambault J. (1990). "Nutritional and hormonal requirements of Ginkgo biloba embryo-derived callus and suspension cell culture". Plant Cell Reports 8:635-638.
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Carrier J, Coulombe P, Mancini M, Neufeld R, Weber M and Archambault J. (1990). "Immobilized Ginkgo biloba cell cultures". in Progress in Plant Cellular and Molecular Biology, Nijkamp H., van der Plas L and van Aartrijk J (ed.) Kluwer Academic Publishers Dordrecht, Boston, London. pp 614-618.
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Carrier J, Luong J and Weber M. (1989). "Substrate consumption of Methylomonas mucosa". Applied Microbiology and Biotechnology 30: 89-91.
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Carrier J, Bogri T, Cosentino G., Guse I, Rakhit S and Singh K. (1988). "HPLC studies on leukotriene A4 obtained from the hydrolysis of its methyl ester". Prostaglandins Leukotrienes and Essential Fatty Acids 34: 27-30.
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Luong J and Carrier J. (1986). "On-line measurement of culture fluorescence during cultivation of Methylomonas mucosa ". European Journal of Applied Microbiology and Biotechnology 24: 65-70.
Oral Presentations
- Carrier DJ and Clausen E. Novel extraction procedures for medicinal plants. Phytopharm 2007, Leiden, The Netherlands June 07 (invited lecture)
- Carrier DJ and Clausen E. Coupling extraction of high value components to pretreatment. American Society of Agricultural and Biological Engineering, Minneapolis, MN June 07
- Carrier DJ and Clausen E. Subcritical water for phytochemical extraction from energy crops. AOCS Québec City May 2007
- Carrier DJ and Clausen E. Liquid fuel production in Arkansas. In service training for Arkansas extension agents, Stuttgart, AR 1/17/07
- Carrier DJ, Clausen E and Nagarajan S. Milk thistle inhibits chemically and cell-mediated oxidization of low density lipoprotein. Natural Health Products Research Society of Canada, Toronto, Canada 3/06
- Carrier DJ, Clausen E, Nagarajan S and King J. Pros and cons of using subcritical water for extraction of medicinal plants. Natural Health Products Research Society of Canada, Toronto, Canada 3/06
- Carrier DJ, Clausen E, Nagarajan S. Silybinin Inhibits Oxidation of Low Density Lipoprotein. American Society of Pharmacognosy, Corvallis, OR 7/05
- Carrier DJ and Clausen E. Extraction of flavonoids from mimosa using water. American Society of Agricultural and Biological Engineering, Tampa, FL 7/05
- Carrier DJ and Clausen E. Medicinal Plants. American Society of Agricultural Engineering, Ottawa, Canada 8/04
- Carrier DJ and Clausen E. Milk Thistle, an interesting herb. Institute of Biological Engineering, Fayetteville, AR 1/04
- Carrier DJ. Dietary supplements- an overview. Northwest Arkansas Dietetic Association, Springfield, AR 9/03
- Carrier DJ. Extraction of specialty chemicals from biomass. S-1007 Biobased Committee, CREES, Washington DC. 5/03
- Carrier DJ. A brief overview of medicinal plants. Cooperative Extension Service ANR Section Leaders Strategic Planning Meeting, Heber Springs, AR 10/02
- Carrier DJ. Silymarin extraction. AIChE, Reno, NV 11/01
- Carrier DJ and Sokhansanj S. Expanding opportunities in Natural Foods. Nutraceuticals/New Direction for Agri-Foods, Winnipeg, Canada 1/00
- Carrier DJ and Sokhansanj. Dehydration of health products. Preservation Technologies for Food, Feed and Fiber, Winnipeg, Canada 11/99
- Carrier DJ, Barl B, Crowe T, Sokhansanj S and Wahab J. Post Harvest Processing of Medicinal Plants. International Herb Conference, East Lansing, MI 7/99
- Carrier DJ, Sjoberg B, Barl B, Crowe T, Sokhansanj S and Wahab J. Post Harvest Processing of Feverfew. CSAE/ASAE Joint Meeting, Toronto Canada 7/99
- Carrier DJ, Kabganian R, Wahab J, Barl B, Crowe T and Sokhansanj. Post harvest processing of Medicinal Plants. 49th Canadian Chemical Engineering Conference, Saskatoon, Canada 10/99
- Carrier DJ, Kabganian R, and Sokhansanj S. Water Removal in Echinacea Processing. Canadian Institute of Food Science and Technology, Kelowna, Canada 6/99
- Carrier DJ, Crowe T and Sokhansanj S. A Prairie Primer to Growing and Marketing Herbs and Spices on the Prairies. Regina, Canada 11/98
- Carrier DJ. Terpenoids in Ginkgo biloba L. Canadian Society of Chemical Engineering, Calgary, Canada 10/94
- Carrier DJ. Pharmaceuticals from plant cell culture. Canadian Society of Agricultural Engineering, Regina, Canada 7/94
- Carrier DJ. Immobilized G. biloba Cell Cultures. VIIth International Congress on Plant Tissue and Cell Culture, Amsterdam, The Netherlands 6/90
Patent
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Cunningham Jim, Carrier Danielle Julie and Dunstan David “Formulation of spruce artificial seed” US Patent Number 5,737,872.

